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mTOR Training for Biceps
Aug 8, 2018
t-nation.com
59:05
mTOR will make you bigger: The mTOR pathway is a central regulator of metabolism with important roles in the function of tissues including liver, muscle, white and brown adipose tissue, and the brain. The activation of TORC1 activation is required for myofibrillar muscle protein synthesis and skeletal muscle hypertrophy in humans in response to both physical exercise and ingestion of certain amino acids or amino acid derivatives. Here is a very good lecture by David Sabatini about the regulation
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Your anabolic switch isn’t getting turned on properly. That switch is called mTOR. It’s your body’s primary sensor for deciding whether to build tissue or break it down. When mTOR detects abundance - amino acids, glucose, ATP - it activates protein synthesis and muscle growth. When it detects scarcity or stress, it flips catabolic and starts breaking tissue down. Everything you do in and out of the gym either turns this switch on or off. Four things activate mTOR. Mechanical tension from lifting
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