It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor -α (CBFα). RUNX proteins form a heterodimeric complex with CBFβ which …

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Jul 17, 2025 · RUNX1 is a transcription factor that forms a complex with the cofactor CBFB. This complex provides stability to the RUNX1 protein which is involved in the generation of …

Runt-related transcription factors (RUNX) are a family of transcription factors that are essential for normal and malignant hematopoietic processes. Their most widely recognized role in …

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Jan 16, 2015 · This Review discusses the many roles of the RUNX family in cancer biology. RUNX proteins belong to a family of metazoan transcription factors that serve as master …