Is Pro Football Talk’s Mike Florio just sort of scatter-shooting when he says he believes San Francisco is suddenly once again is a top-five powerhouse in its conference?

The San Francisco 49ers need star running back Christian McCaffrey to be healthy for the entirety of this season to recapture the NFC West crown.

How does the classic saying go? Look good, feel good, play good? That expression cannot be more true than it is in the NFL. Throughout the league’s 100+ year ...

Snow showers are expected in Orchard Park during the game, with a low around 26 degrees. Wind gusts could reach 48 mph. A 54-mile-per-hour wind gust was reported in Buffalo on Monday afternoon, a ...

For close to two decades starting in 2000, St. John Fisher University signed several different multiple-year contracts with the Buffalo Bills to serve as the home of the team’s summer training camp.

Heliot Ramos doubled home two runs to highlight San Francisco's decisive seventh inning after an earlier two-run single, and the Giants rallied to beat the Boston Red Sox 9-5.

Not one, but two national analysts are bullish on the Buffalo Bills' offense. ESPN analysts Mina Kimes and Ben Solak ranked their Top 10 offenses on The Mina Kimes Show, with both NFL experts ...

Philadelphia Eagles' multi-time Super Bowl Champion Brandon Graham recently delivered his honest thoughts on the San Francisco 49ers' trade pickup, Bryce Huff.

As the canopy is completed on top of the Buffalo Bills new stadium, the days of the team calling for snow shovelers to help clear the stadium may soon become a thing of the past. That’s because ...

In a nationally televised game featuring the Bills against the visiting San Francisco 49ers, NBC viewers were treated to a winter wonderland. Lake effect conditions in western New York had state ...

On Thursday, the Buffalo Bills wrapped up their three-day mandatory minicamp at the team’s practice facilities in Orchard Park, NY, concluding phase three of the team’s offseason workout program.

They are from London, Ont. He loves the Bills, and she loves him, so now she loves the Bills, too. We met them by chance as my wife, Carol, and I were taking a tour of the Colosseum some weeks ago.