The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

The San Francisco 49ers are reportedly expected to lean on rookie running back Isaac Guerendo for the remainder of the 2024 ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Christian McCaffrey, at the premature end of a season that started late, too, waxed philosophical in a social media post on ...

With their top two options sidelined, the expectation was that rookie Isaac Guerendo would lead the backfield for the ...

McCaffrey's old backfield mate discussed the trials and tribulations of a season-ending injury on his podcast.

Having suffered a knee injury that landed him on injured reserve during a snowy loss to the Bills on Sunday night, 49ers ...

San Francisco’s star running back McCaffrey is sitting on injured reserve once again, with the postseason getting ever nearer ...

San Francisco 49ers running back Christian McCaffrey was the near-consensus No. 1 pick in fantasy football drafts. However, ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...