Gene dysregulation in trisomy 21 can cause disorders of genes that are members of the heat-shock proteins (HSPs) family and contribute to the early onset of Alzheimer’s disease (AD) in Down syndrome ...

To celebrate the groundbreaking research of 2025 Drake Award recipients Dr. David Deamer and Dr. John Baross, the SETI Institute commissioned bioartist Dr. Jennifer Willet to create a unique artwork ...

miRNAs are small non-coding RNAs that regulate gene expression and influence key developmental processes. In plants, these molecules are produced through a multistep biogenesis pathway involving the ...

While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

aRheumatology Service, Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Córdoba, Córdoba, Spain Antiphospholipid syndrome is a rare ...

Tumor-suppressive miRNAs inhibit oncogenic pathways, preventing cancer progression, while oncogenic miRNAs promote tumor growth by targeting tumor suppressor genes. miRNA, microRNA. Lung cancer (LC) ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

Double-stranded RNA (dsRNA) has emerged as key player in gene silencing for the past two decades. Tailor-made dsRNA is now recognized a versatile raw material, suitable for a wide range of ...

ABSTRACT: Objective: This study aimed to identify differentially expressed microRNAs (miRNAs) using microarray and to predict special target genes using bioinformatics methods in the neonatal rat ...