Next-generation sequencing (NGS) has transformed genomic research and healthcare by enabling the rapid and cost-effective sequencing of DNA and RNA, surpassing traditional techniques such as Sanger ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA ...

Single-cell RNA sequencing of thousands of yeast progeny reveals how gene expression differences and heritability drive phenotypic diversity.

A total of 249 disease targets were identified through single-cell RNA-seq and bulk RNA-seq analyses. Functional enrichment analysis highlighted the involvement of extracellular matrix organization, ...

Accurate cell classification is crucial but expensive for large-scale single-cell RNA sequencing (scRNA-seq) analysis. Gene selection (GS) emerges as a pivotal technique in identifying gene subsets of ...

In this study, we used RNA-Seq, computational analysis, and experimental approaches to characterize the expression and localization of uniquely mapping human TEs in response to IAV infection.

Scripts for "Current best-practices in single-cell RNA-seq: a tutorial" Note The "current" best practices that are detailed in this workflow were set up in 2019. Thus, they do not necessarily follow ...

Single-cell RNA sequencing atlas of intestinal injury induced by different clinical treatments in colorectal cancer patients.. If you have the appropriate software installed, you can download article ...

This scarcity likely arises because the STB, being a large single cell, is excluded during the single-cell isolation and size filtration steps required for the 10 x Genomics microfluidics pipeline.

MicroRNAs (miRNAs) play important regulatory roles in biology. Direct sequencing of miRNAs in full-length can reveal comprehensive information on their sequences, abundance, and modifications, which, ...