Cancer biology research increasingly recognizes the profound heterogeneity and plasticity of cancer cells. These cells can transition dynamically between ...

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart ...

It’s important to understand what over-the-counter biological age test kits can — and can’t — do before buying them.

But their free-eating diets and limited physical activity contribute to a disruption of life rhythms, such as circadian ...

The brain is the most complex organ in the human body. Different parts of the brain perform a variety of functions, all of ...

Researchers have mapped how "histone bivalency" acts as a molecular clock for brain development. By holding genes in a poised state, this mechanism ensures neurons mature only after completing ...

A randomized clinical trial found that daily multivitamin–multimineral supplements slightly slowed some DNA-based markers of biological aging in older adults.

Aging may "erase" the epigenetic markers that control gene expression in the brain, and this may snowball to cause unintended consequences, a new mouse study suggests.

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...

Diet can leave lasting epigenetic marks that reshape gene expression, metabolic pathways, and disease susceptibility across the lifespan. These diet-driven molecular changes may create a form of ...

This study presents an advance in efforts to use histone post-translational modification (PTM) data to model gene expression and predict epigenetic editing activity. Such models are broadly useful to ...

New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in the parents’ lysosomes that promote longevity are transferred to their offspring.