From medicine to agriculture and aquaculture, bacteriophages are poised to have a huge global impact. As viruses which target ...

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell’s protein-making machinery. rRNA accounts for much of the RNA in a cell, and it’s crucial for life. “It’s ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...

This work introduces an important new method for depleting ribosomal RNA from bacterial single-cell RNA sequencing libraries, demonstrating its applicability for studying heterogeneity in microbial ...

In this manuscript, Yan and colleagues introduce a modification to the previously published PETRI-seq bacterial single cell protocol to include a ribosomal depletion step based on a DNA probe set that ...

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes might be enough to alter the binding site of ...

An agar plate containing colonies of Klebsiella pneumoniae bacteria, one of the drug-resistant strains the synthetic compound cresomycin has shown to combat. Credit: Myers Research Group Cresomycin, a ...

A new antibiotic overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis. A new antibiotic created by Harvard ...

A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis. A team led ...