Open Heart

Causal relevance of clonal haematopoiesis with cardiac disease and adverse remodelling: a Mendelian randomisation study

Background Many observational studies highlight clonal haematopoiesis (CH) as a novel determinant of cardiovascular disease ...
openheart.bmj

Effectiveness of an impedance cardiography guided treatment strategy to improve blood pressure control in a real-world setting: results from a pragmatic clinical trial

Objective To test the effectiveness of an impedance cardiography (ICG) guided treatment strategy on improving blood pressure (BP) control in real-world clinical practice. Design A single-centre, ...
Open Heart

Association between atherogenic index of plasma and incident aortic disease: a population-based prospective analysis

Objective To clarify whether atherogenic index of plasma (AIP), a comprehensive indicator reflecting both the protective and ...
openheart.bmj

Phenotyping of patients with mild pulmonary hypertension

Background Revised haemodynamic criteria for pulmonary hypertension (PH)—mean pulmonary artery pressure (mPAP) >20 mm Hg and pulmonary vascular resistance (PVR) >2 Wood Units (WU)—have defined new ...
openheart.bmj

Long-term effects on cardiac function and symptoms in patients with myocarditis following COVID-19 vaccination: the ECHOVID-19 Long-term Study

Background The long-term effects of myocarditis following COVID-19 vaccination on cardiac function and symptoms remain unclear. Purpose To assess the long-term effects of myocarditis following ...
openheart.bmj

Clinical impact of mean pulmonary arterial pressure after balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension

Background Balloon pulmonary angioplasty (BPA) improves haemodynamics in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Previous studies on BPA have set the treatment ...
openheart.bmj

Deep learning-based prediction of future myocardial infarction using invasive coronary angiography: a feasibility study

Background Angiographic parameters can facilitate the risk stratification of coronary lesions but remain insufficient in the prediction of future myocardial infarction (MI). AIMS We compared the ...
openheart.bmj

Four-dimensional flow provides incremental diagnostic value over echocardiography in aortic stenosis

Aims Four-dimensional flow cardiovascular MRI (4D flow CMR) has emerged as a promising technique for assessing aortic stenosis (AS). This study aimed to evaluate the agreement between 4D flow CMR and ...
openheart.bmj

New score for assessing bleeding risk in patients with atrial fibrillation treated with NOACs

Background Information is needed on bleeding risk factors specific for patients with atrial fibrillation (AF) treated with non-vitamin K oral anticoagulants (NOACs). We aimed to identify risk factors ...
openheart.bmj

Clinical use and impact of mechanical circulatory support for myocardial infarction-related cardiogenic shock in the Netherlands: a registry-based propensity-matched analysis

Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch ...
openheart.bmj

Mechanical circulatory support in cardiogenic shock: translating trial evidence into real-world practice

While iterative developments have improved outcomes of patients with myocardial infarction, mortality in patients with acute myocardial infarction cardiogenic shock (AMI-CS) remains stubbornly high.
openheart.bmj

Diagnostic accuracy in coronary CT angiography analysis: artificial intelligence versus human assessment

Background Visual assessment of coronary CT angiography (CCTA) is time-consuming, influenced by reader experience and prone to interobserver variability. This study evaluated a novel algorithm for ...