The Michigan Wolverines face the Purdue Boilermakers on Saturday night at Michigan Stadium. The Wolverines are expected to steamroll the Boilermakers, according to the newly released betting odds.

The fiasco that was the Boilermakers' final offensive play in a 27-24 loss to Rutgers at Ross-Ade Stadium will be the play people remember, but it wasn't the reason Purdue didn't win. That Ryan Browne completion to himself turned fumble did in some ways epitomize Purdue's season, which now includes six losses in a row.

The spread has opened for next weekend's Big Ten matchup between Purdue and Michigan. The Wolverines enter the game as heavy favorites over the Boilermakers.

The Boilermakers had an opportunity for a game-winning drive, but fumbled that opportunity away and likely their shot at ending a Big Ten losing streak this season.

Rutgers wide receiver Kj Duff (8) is tackled by Purdue defensive back Smiley Bradford (1) during the second half of an NCAA college football game in West Lafayette, Ind., Saturday, Oct. 25, 2025. Credit: AP/Michael Conroy

Purdue running back Devin Mockobee was wide open, scoring on an easy touchdown pass from Malachi Singleton in Saturday's game vs. Rutgers.

Purdue football came out strong early in its homecoming matchup, taking an early lead and looking to be in position to pick up its third win of the year. A fourth quarter collapse ended these hopes as Rutgers was able to flip the game with a last second kick.