Up to three feet of snow could batter the Buffalo Bills’ stadium this weekend, where the San Francisco 49ers are scheduled to ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

Purdy missed the 49ers' Week 12 contest versus the Green Bay Packers last Sunday with a right shoulder injury—a game San ...

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the ...

By kickoff, there could be feet of snow on the ground south of Buffalo and nearly two feet in Orchard Park. A lake effect ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

Bonnie is a sweet cattle dog mix and she knows how to get a team moving! Watch as she makes her choice on the Bills vs 49ers ...

ORCHARD PARK, N.Y. -- Josh Allen’s latest kneel-down had nothing to do with football.