The 49ers (5-3) and the Giants (2-6) renew a storied rivalry Sunday at MetLife Stadium as each cope with the losses of big-time stars.

San Francisco 49ers QB Brock Purdy isn't all the way back from his "annoying" toe injury, but he will be available off the bench behind Mac Jones against the New York Giants on Sunday.

With the Giants ranking 27th in points allowed and 29th in yards allowed, the question now seems to be, how much worse can it ...

While the 49ers wait to see how Brock Purdy responds from practice, Mac Jones is otherwise preparing for a fifth straight ...

New England Patriots quarterback Drake Maye launches a dime to wide receiver Kayshon Boutte for a 39-yard touchdown against ...

The Panthers went back to a backfield split in Week 7 with Dowdle and Chuba Hubbard. However, Dowdle still finished with 79 ...

The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They may be projecting the injuries to finally catch up to the 49ers. If the ...

Mac Jones is likely to feature again at quarterback for the San Francisco 49ers in Week 7. Everything points in that direction, as head coach Kyle Shanahan stated that both Mac Jones and Brock Purdy ...

San Francisco 49ers quarterback Mac Jones (10) passes the ball over Tampa Bay Buccaneers linebacker Anthony Nelson, bottom, during the first half of an NFL football game in Tampa, Fla., Sunday, Oct.

Brock Purdy remained limited in Thursday’s practice, while Mac Jones returned to full participation. Purdy is working his way back from a toe injury that has limited him to two games this season.

Mac Jones of the San Francisco 49ers passes the ball while being hit by Anthony Nelson of the Tampa Bay Buccaneers during the second quarter. Mike Ehrmann / Getty Images It was another gutsy effort by ...