A biobank of 256 patient-derived tumour organoids, combined with genome-wide CRISPR-Cas9 screening, has produced a detailed ...
A preclinical study has identified lysyl oxidase as an intracellular survival factor in triple-negative breast cancer, with ...
As NAMs become more widely used in drug discovery, assays must meet the demands of more complex models. Discover six ...
A preclinical study combining chemically modified suppressor tRNAs with inhaled lipid nanoparticles has restored functional ...
As sequencing continues to grow in importance across biotherapeutic discovery and development, where can it make the biggest ...
A metabolic signal detectable in patient blood has been linked to ALS progression rate and survival, with preclinical data ...
A preclinical study has identified a metabolic vulnerability in aggressive MYC-driven breast cancers, with researchers ...
A new review published in the European Journal of Pharmaceutics and Biopharmaceutics argues that no single local ...
St Jude researchers have demonstrated that deleting the Regnase-1 gene from CAR T cells significantly improves tumour control ...
A structure-guided peptide vaccine targeting PCSK9 has reduced LDL cholesterol and atherosclerotic plaque burden in mouse ...
A preclinical study has identified a subset of exhausted, LAG3-expressing T cells capable of migrating out of tumours to ...
Five leading cancer researchers from across genomics, proteomics, cell biology, chemical biology and gene therapy dig into ...
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