Blood donors in Southern California can earn a ticket to SeaWorld San Diego's Howl-O-Scream Halloween event this fall through ...

An investigation is underway after a San Diego PD officer was involved in a crash overnight. According to preliminary ...

Sweeping Change is assembling a medical team for a mission to flood-ravaged Nepal, as a volunteer with the group grieves six ...

A woman who fatally stabbed her wife, a veteran state firefighter, at their Ramona home, is slated to be sentenced Wednesday ...

Despite Fernando Tatis Jr.'s two home runs, the Padres came up short in Cincinnati, dropping them to 1-4 on their six-game ...

The FAA Tuesday awarded the San Diego County Regional Airport Authority $15.3 million for its Quieter Home Program to provide ...

The head of Monarch School told ABC 10News that the suspicion of mold occurred Thursday night. The pivot to temporarily close ...

A pedestrian lost his life over the weekend to a late-night hit-and-run in Escondido, authorities reported Monday.

UC San Diego researchers have received an $11.3 million contract to develop "smart" red blood cells to give soldiers an ...

Jose De Jesus Anguiano offered money, marijuana and alcohol to four minors between the ages of 13 and 17 as part of attempts to coerce them into engaging in sexual acts with him, authorities said.

The San Diego Padres are bringing in reinforcements for the stretch run with the promotion of top prospect Ethan Salas.

Tuesday marks the first day that San Diegans can hail a public ride in an autonomous Waymo vehicle. Waymo is expanding its ...