gut.bmj

Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure

Background Why alcohol-associated liver disease (ALD) resolves after abstinence in most people but progresses to liver failure in others remains poorly understood. Experimental models show that ...
gut.bmj

Repositioning dual GLP-1/GIP receptor agonists for the treatment of colitis and colitis-associated tumourigenesis

We read with great interest the commentary by Benson Massey, which raises concerns about the recent widespread use of glucagon-like peptide-1 (GLP-1) agonists.1 We offer an alternative perspective and ...
gut.bmj

From preclinical phase of Crohn’s disease to postoperative recurrence: shared mechanisms and potential interventions

Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with high risk of surgery. Despite advances in medical treatment, of those patients who undergo ileocolonic ...
gut.bmj

Participation and yield of a population-based colorectal cancer screening programme in China

Correspondence to Professor Min Dai, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing ...
gut.bmj

Emerging treatment options for extraintestinal manifestations in IBD

Correspondence to Dr Stephan R Vavricka, Gastroenterology and Hepatology Center, Zurich, Switzerland; stephan.vavricka{at}usz.ch; Dr Thomas Greuter, Department of Gastroenterology and Hepatology, ...
gut.bmj

Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review

4 Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia Correspondence to Dr Hashem B El-Serag, Section of Gastroenterology and ...
gut.bmj

Nationwide gastric cancer prevention in China, 2021–2035: a decision analysis on effect, affordability and cost-effectiveness optimisation

Correspondence to Professor Jingmei Jiang, Department of Epidemiology and Biostatistics, Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medical Sciences, ...
gut.bmj

Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19

We read with great interest the article published by Zuo et al , which highlighted the presence of SARS-CoV-2 RNA in stool samples during active and convalescence phases of COVID-19 infection.1 ...
gut.bmj

Submucosal steroid pre-injection strategy to prevent oesophageal stricture after circumferential endoscopic submucosal dissection

Correspondence to Professor Xin Yang, Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; yxin100{at}hospital.cqmu.edu.cn Oesophageal ...
gut.bmj

Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study

Background and aims: Melatonin, a sleep promoting agent, is involved in the regulation of gastrointestinal motility and sensation. We aimed to determine if melatonin was effective in improving bowel ...
gut.bmj

Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons

Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Correspondence to Dr Rina Rosin-Arbesfeld, Department of Anatomy and Anthropology, Sackler ...
gut.bmj

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

Background and aims A general dysbiosis of the intestinal microbiota has been established in patients with Crohn's disease (CD), but a systematic characterisation of this dysbiosis is lacking.