Objective This study aimed to compare 25-hydroxyvitamin D (25-(OH)D) levels and peripheral lymphocyte subsets between ...
Objectives DNASE1L3 deficiency is a rare monogenic cause of early-onset SLE and hypocomplementaemic urticarial vasculitis ...
Objective This study aimed to assess the efficacy and safety of telitacicept combined with standard of care (SoC) as induction therapy for proliferative lupus nephritis (LN) patients in a real-world ...
Background The short-term and long-term outcome of inflammatory neuropsychiatric SLE (NPSLE) with immunosuppressive treatment is largely unknown. We used clinical data from our tertiary referral ...
Objective Identify whether changes in metabolite abundance are associated with SLE flare remission and changes in DNA methylation (DNAm). Methods 40 multiethnic patients with SLE were recruited during ...
The case for early biologic therapy in systemic lupus erythematosus (SLE) is intuitively appealing but requires closer scrutiny. First, ‘early’ is poorly defined with UK survey data showing a mean ...
Objectives Cardiovascular disease is a leading cause of morbidity and mortality in systemic lupus erythematosus (SLE), largely driven by endothelial dysfunction. Belimumab, a monoclonal antibody ...
Systemic lupus erythematosus (SLE) is a profoundly heterogeneous disease in which clinical phenotype emerges from the interplay of autoantibody profiles, organ involvement, cytokine signatures, ...
Objectives We examined the association between systemic lupus erythematosus (SLE) and the risk of heart failure and cardiomyopathy (HF/CM) and assessed whether initiation and duration of ...
Case 1: A 43-year-old Caucasian woman with fever, acute tonsillitis, nausea and diarrhoea A 43-year-old Caucasian woman with SLE was admitted at the Hospital Clínic of Barcelona with fever, acute ...
Objective To characterise the safety and efficacy of anifrolumab in active lupus nephritis (LN) through year 2 of the phase II randomised, double-blind Treatment of Uncontrolled Lupus via the ...
22 Historical aspects of B-cell depletion in SLE (8 October, 2025) ...
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