G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a ...

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping.

When activated in ovarian cancer cells, the receptor for the body's primary stress hormone alters the tumor environment in ...

Study reveals how Golgi proteins GOLPH3 and MYO18A route RTKs to the cell surface, setting oncogenic signaling strength and ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Caveolin‑1 is a membrane-associated protein expressed in many cell types that plays a key role in modulating inflammatory ...