This new information about how transcription factors work may have implications for RNA-based therapeutics, and has broadened our understanding of how genes activity is regulated. Previous work has ...

While the biology of CTCF has been extensively studied, how the different domains (parts) of CTCF function in relation to transcription regulation remains unclear.

Bacterial transcription is a production line of copying over genetic instructions from double stranded DNA to produce RNA, which is then used for the subsequent production of proteins that the ...

The study, published today in Genome Biology, paves the way for more clear, nuanced studies of CTCF. Transcription is an essential biological process where DNA is copied into RNA.

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

Lacra Bintu discusses how synthetic transcription factors can be used to control gene expression and epigenetic memory.

Ankylosing spondylitis (AS) is increasingly recognized as an independent risk factor for premature myocardial infarction (MI) ...

The interplay between the circadian clock, intestinal stem cell niche, and epithelial cell fate is shaping our understanding ...