Daratumumab, a human IgG1κ monoclonal antibody targeting CD38, is used to treat multiple myeloma. We describe successful treatment with daratumumab in a case of treatment-refractory pure red-cell ...
Patients with elevated anti-HLA antibodies experienced significantly prolonged time to transplant — a median of 120 days ...
Acute immune intravascular hemolysis can also represent a delayed hemolytic transfusion reaction. This is a consideration in this case, because the patient received 2 units of red cells 2 weeks before ...
Existing monoclonal antibody development technologies, such as hybridoma technology, suffer from a loss of diversity due to cell fusion efficiency, and phage display technology creates antibodies ...
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