Scientists found a virus-like living entity in human bodies named "obelisks" - small loops of RNA, each a thousand genetic ...

Achieved proof-of-mechanism for Wave’s RNA editing platform; restoring levels of wild-type (edited) M-AAT that are consistent with the heterozygous “MZ” genotype with low risk of AATD lung and liver ...

A groundbreaking study reveals that human cells initiate self-destruction processes when viruses disrupt RNA production, offering new insights into innate antiviral defenses. Conducted and reported on ...

Wave Life Sciences' WVE-006 shows RNA editing in AATD patients, reaching over 60% of total AAT protein at day 15. WVE-006 has been well-tolerated with no serious adverse events; multidose data ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message ...

They observe how the mobile DNA LINE-1 copies its sequence in human cells, revealing the precise mechanism of the ORF2p gene.

CREATE Medicines, Inc. (formerly Myeloid Therapeutics) today announced new preclinical data for RetroT, the company's fully RNA-encoded, site-specific gene-integration system, presented at the Cold ...

Stem cells, which drive regeneration, require a microenvironment in tissue called a niche, but not so much in this ...

A paper in Molecular Biology and Evolution finds that the relatively high rate of autism-spectrum disorders in humans is likely due to how humans evolved in the past. The paper is titled "A general ...