In a multicenter, double-blind trial, we randomly assigned mechanically ventilated adults with sepsis to receive dexmedetomidine (0.2 to 1.5 μg per kilogram of body weight per hour) or propofol (5 to ...

In critically ill patients, sedation with alpha-2 adrenergic receptor agonists such as dexmedetomidine and clonidine, introduced within 48 hours of initiating mechanical ventilation, was not superior ...

While the use of propofol is common in dentistry, researchers are fine-tuning ways of using it effectively. Proper sedation and patient comfort can depend on fairly large doses of propofol when it is ...

Propofol is one of the most used drugs for general anesthesia, but the findings of a new study suggest that the medication may also be beneficial for conscious sedation. Researchers from the U.K.

Researchers conducted a randomized controlled phase 3 trial across 29 medical centers in China between March and September 2024 to assess the efficacy and safety of remimazolam tosylate vs propofol ...

Detection of serrated polyps during colonoscopy improved significantly with the use of propofol-based versus conventional sedation, data from a large registry showed. The detection rate increased from ...

Dreaming is almost five times more common with propofol infusion than with midazolam in patients receiving spinal anesthesia with deep sedation, according to a study published in the April 2011 issue ...

In patients undergoing colonoscopy to screen for colorectal cancer, deeper sedation using the anesthetic drug propofol may improve detection of "serrated" polyps - a type of precancerous lesion that ...