When Joseph Broderick was a college sophomore in 1975, stroke treatment was a waiting game. Doctors could diagnose a stroke but couldn’t stop it. There were no scientifically proven therapies, no ...

There is now good evidence that a series of genetic alterations in both dominant oncogenes and tumour suppressor genes are involved in the pathogenesis of human colorectal cancer (CRC). Activation of ...

The clot-busting drug tissue plasminogen activator (tPA) is currently the only FDA-approved therapy for acute stroke. However, increasing evidence suggests that tPA can also contribute to excitotoxic ...

Patients with stroke who receive intra-arterial thrombolysis after thrombectomy are more likely to achieve superior 90-day ...

Please provide your email address to receive an email when new articles are posted on . NEW YORK — Vitrectomy using balanced saline solution without tissue plasminogen activator is effective for ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 3 (1990), pp. 1114-1118 (5 pages) To improve the efficacy of plasminogen activators, we produced a ...

A new study published online in the Journal of Trauma and Acute Care Surgery in March 2020 reports that the anticoagulation drug tPA could be a potential aid in managing respiratory failure in ...

Is there a contraindication to the use of recombinant tissue plasminogen activator (r-TPA) in a patient who is taking clopidogrel or clopidogrel and aspirin, or ticlopidine or ticlopidine and aspirin?

TISSUE PLASMINOGEN ACTIVATOR (TPA) INJECTED INTRAVENOUSLY within 3 hours of symptom onset has emerged as a treatment option for acute ischemic stroke. Although controversial and not universally ...

SEATTLE--(BUSINESS WIRE)--According to Coherent Market Insights, the global tissue plasminogen activator market is estimated to be valued at US$ 2,455.4 million in 2020 and is expected to exhibit a ...

Abbreviations: CLT, clot lysis time; ETP, endogenous thrombin potential; PAI-1, plasminogen activator inhibitor-1; TAFI, thrombin activatable fibrinolysis inhibitor; tPA, tissue plasminogen activator; ...