Penicillinase is an enzyme that acts on the β-lactam ring of penicillin to convert penicillin into penicillic acid, which has no antibacterial activity. A variety of penicillin-resistant bacteria can ...

WITH the long-acting depot penicillins in general use today, prolonged blood levels also prolong the sensitivity reactions when they occur. The use of ACTH and cortisone as anti-inflammatory agents to ...

The in-vitro antigonococcal activity of enoxacin was measured by a broth microdilution method. Comparisons were made with five clinically relevant marketed drugs against 23 clinical isolates of ...

WHILE studying the kinetics of penicillinase inactivation of various penicillins, it became evident that a penicillinase-susceptible penicillin, such as benzyl-penicillin, behaved differently from ...

WHEN the results of a gram stain or culture of material in a serious case of staphylococcal infection become known, and before the susceptibility of the organism has been determined, the physician is ...