The attachment of sister kinetochores to microtubules from opposite spindle poles is necessary for accurate chromosome segregation during cell division. Unattached kinetochores activate the cell-cycle ...

Cell division is essential for the correct transmission of genetic information. Each chromosome within a plant contains a ...

In human cells, lengthy strands of DNA have to be carefully organized and compacted so they'll fit into the nucleus; our genome is arranged into chromosomes that have to be duplicated each time a cell ...

Which end of the kinetochore fibre shortens and whether shortening actively drives or passively permits polewards chromosome movement represent enduring problems in understanding anaphase ...

(Phys.org) -- With the first-ever three-dimensional image of an isolated kinetochore – the bulky molecular machine that connects a chromosome to the long, thin microtubules that tug it to one end of a ...

Thousands of our cells successfully divide every day. They replicate their DNA and then separate so that each of the new cells has the same complement of chromosomes. If the process goes wrong and ...

Osaka, Japan – During cell division, chromosomes, i.e., molecules containing our genetic material, must be properly replicated and segregated so that each daughter cell receives a complete and ...

Cell division builds our bodies, supplying all cells in our tissues and organs, from the skin to the intestine, from the blood to the brain. It not only allows these organs to grow, but also to ...

As a cell divides, its DNA -the genetic material- is duplicated and condensed into structures called chromosomes, which are carefully organized and distributed so that each daughter cell acquires a ...

Robert Blackwell, Oliver Sweezy-Schindler, Christopher Edelmaier, Zachary R. Gergely, Patrick J. Flynn, Salvador Montes, Ammon Crapo, Alireza Doostan, J. Richard ...

Centromeres are the chromosomal domains at which the kinetochore, a protein complex required for the correct separation of chromosomes during mitosis and meiosis, is assembled. The incorporation of ...

Crowning a quest into a very well-guarded secret: Structure of the kinetochore corona finally revealed Date: April 8, 2022 Source: Max Planck Institute of Molecular Physiology Summary: During cell ...