Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to be associated with neurodegenerative disorders. Corresponding author Kai ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

The c-Jun N-terminal kinases (JNKs) form a subgroup of mitogen-activated protein kinases that respond to metabolic and inflammatory stress signals. In obesity, excess nutrients and adipose tissue ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Study: Personalized molecular signatures of insulin resistance and type 2 diabetes. Image credit: Microgen/Shutterstock.com A recent study, published in the journal Cell, utilized cutting-edge ...

Growing evidence suggests it takes a sustained viral infection in the right genetic environment to lead to type 1 diabetes.

A Brazilian study published in the journal Nutrients suggests that fish oil can weaken insulin resistance and reduce glucose intolerance by modulating the body's inflammatory response. The findings of ...

Metformin remains a leading candidate for pharmacologic longevity intervention Metformin continues to occupy a unique ...

Disease-modifying therapies for type 1 diabetes are beginning to move care beyond insulin replacement by targeting immune ...