Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition. Huntington's is caused by a mutation in the gene ...

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The appearance of clots of abnormal proteins inside neurons is characteristic of many neurodegenerative diseases. These intracellular inclusions were long presumed to be toxic manifestations of ...

Dense protein aggregates called inclusion bodies are found in the neurons of those suffering from any of several neurodegenerative disorders including Alzheimer, Parkinson, and Huntington diseases.