Shotgun sequencing can reassemble a badly fragmented genome from overlapping DNA segments of various lengths—but it struggles with the larger fragments, tens of thousands of base pairs long.

The Age of AI will rely on massive volumes of data that can be easily stored and retrieved—and bioscience may have an ...

Sequencing DNA is very, very simple: there's a molecule, you look at it, you write down what you find. You'd think it would be easy -- and it is.

As a DNA residue traverses the pore, it disrupts the current to produce a characteristic signal that can be decoded into a sequence of DNA bases. Proteins, however, are harder to crack.

These computing resources are needed to power the DNA assembly and analysis, the computer-science heavy final step in the sequencing process. “It was really cool to see how sequencing goes from a wet ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

Ancient DNA is a new and rapidly growing field, with a Nobel Prize awarded in 2022 to Svante Pääbo for his foundational work. Using samples taken from skull bones or teeth, aDNA researchers can ...