For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate constellations of DNA variants acting together in specific cells. Now a new ...

The ability of different genetic variants—changes to one or more building blocks of DNA—to cause disease, and to what extent, has historically been opaque. Geneticist and Crick group leader Greg ...

Engineered proteins that can cross the blood–brain barrier represent a reliable and non-invasive way to map gene expression in the brains of large animals. Gene therapy has been successfully used to ...