DNA methyltransferases (MTases) play a pivotal role in epigenetic regulation by catalysing the transfer of methyl groups to specific DNA bases. This modification is instrumental in regulating gene ...

An enzyme implicated in osteoporosis, arthritis, atherosclerosis and cancer metastasis – cathepsin K -- eluded reliable detection in laboratory experiments in the past. Now, a research team at the ...

AMSBIO (Oxford, UK) has launched a new range of deubiquitinating (DUB) enzyme assay kits supplied in a convenient and easy-to-use 96-well assay format. With minimal setup required and no need for ...

Methylation is a key post-translational modification (PTM) of mammalian proteins and nucleic acids where unique enzymes known as methyltransferases (MTases) transfer methyl groups to a variety of ...

This article describes a simple method to determine the optimum pH for the activity of one enzyme in a coupled enzyme assay. Decoupling of the two-step reaction is achieved by heat denaturing the ...

Researchers at Arizona State University have developed a breakthrough diagnostic tool that could transform how quickly and reliably we detect illnesses like COVID-19, Ebola, AIDS or Lyme disease. The ...

Creative Enzymes stands as a leading provider of enzyme-related services and solutions. Committed to innovation and excellence, the organization supports research in enzymology and biotechnology by ...

Today's gold standard for COVID diagnostics is qRT-PCR, but turnaround is typically more than a day. Newer assays using CRISPR enzymes require initial amplification of RNA, requiring special equipment ...

Three Prime Repair Exonuclease 1 (TREX1) is an essential component of the innate immune response. It is the primary exonuclease responsible for the degradation of cytosolic DNA. The reduction of ...