UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is ...

Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

Within aging organisms, cells slowly lose their youthful precision: Membranes stiffen, repair systems malfunction, and proteins begin to misfold and pile up. One of the cell organelles that ...

An international team, including scientists from Leipzig University, has gained important new insights into the regulation of ...