The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...

The ER normally appears like a huge, dynamic net, so as soon as Lippincott-Schwartz saw the structures, she knew her lab needed to figure out what they were for. "In science, structure is function," ...

Caption The ER (in yellow) almost covers the entire expanse of a cell. (left) Tube-like ER structure at the cell periphery near a convex shaped gap boundary; (right) Flattened sheet-like ER structure ...