Somatic mutations, the DNA changes that occur as our bodies grow and age, not only hold an important key to cancer but are ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

Researchers at Beijing Genomics and IMDEA Nanociencia institutes have introduced a novel method that could significantly accelerate efficiency and reduce the cost of handling fluidics in DNA ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

The US Patent and Trademark Office's Patent Trial and Appeal Board rejected a challenge from Guardant Health (GH) on a DNA ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...

Definition: DNA amplification is the laboratory process of making many copies of a selected DNA sequence from a very small starting amount. It allows DNA that would otherwise be too scarce to detect ...

Long-read DNA testing diagnosed 35% of previously unsolved inherited muscle disease cases, detecting complex genetic changes ...

DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...