For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...
The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell division ...
Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...
Researchers at Baylor College of Medicine have discovered that certain p53 mutants hijack the DNA replication machinery ...
“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...
The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to ...
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