Semiconservative replication was not the only model of DNA replication proposed during the mid-1950s, however. In fact, two other prominent hypotheses were put also forth: conservative replication ...

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...

A centrifuge was used to separate DNA molecules labeled with isotopes of different densities. This experiment revealed a pattern that supports the semiconservative model of DNA replication.

More information: Bruce Stillman et al, Mechanisms for licensing origins of DNA replication in eukaryotic cells, Nature Structural & Molecular Biology (2025). DOI: 10.1038/s41594-025-01587-5 ...

By using some quasi-renewal-like equations and functional differential equations, we explicitly compute the Laplace transforms of some random variables introduced by Cowan and Chiu in modeling the ...

Samuel Schindler, Model, Theory, and Evidence in the Discovery of the DNA Structure, The British Journal for the Philosophy of Science, Vol. 59, No. 4 (Dec., 2008), pp. 619-658 ...

More information: Tyler M. Maclay et al, The DNA replication checkpoint targets the kinetochore to reposition DNA structure-induced replication damage to the nuclear periphery, Cell Reports (2025).

The study, published online in Cell on August 4, achieves multiple types of precise DNA manipulations ranging from kilobase to megabase scale in higher organisms, especially plants.