Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what the mechanisms, or the causes behind those specific genetic changes, are.

As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes. A new study used single cell sequencing ...

Chromosomal aberrations, encompassing both structural and numerical chromosome abnormalities, are fundamental indicators of genomic instability with far‐reaching implications for cancer risk. These ...

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues. Subscribe to our ...

Researchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a ...

New @hopkinskimmel research finds extra copies of chromosome 1q may drive the earliest stages of pancreatic cancer. › ...

Genetic testing for chronic myeloid leukemia (CML) can tell doctors if someone has leukemia, what type they may have, and whether treatment is working. The tests look for atypical changes in certain ...

Ewing sarcoma develops due to genetic causes that include changes to a person’s DNA and chromosomes. It more often affects teenagers and young adults, males, and white people. The exact cause of Ewing ...

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues. When pregnancy loss occurs ...