From the point of view of patient care, your recent debate over classical genetics 123 makes it clear that any form of current classical one-by-one gene status assessment will not be adequately ...

It’s among the most well-known rules in modern biology: Genetic information flows in one direction, from DNA to RNA to protein. But a recent discovery complicates and adds nuance to this so-called ...

DNA to RNA to Protein: This is the Central Dogma, a term coined by Francis Crick in 1958. Since the discovery of the helical structure of DNA, scientists began to elucidate the value of that structure ...

Kenneth Eward/BioGrafx/Photo Researchers Inc. Nearly two decades ago, Paul H. Silverman testified before Congress to advocate the Human Genome Project. He later became frustrated when the exceptions ...

The central dogma of molecular biology is key to understanding the relationship between genotype and phenotype, although it remains a challenging concept to teach and learn. We describe an activity ...

For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained ...

According to this line of thinking, making twice as many mRNAs would yield twice as many proteins; however, when considered at a systems level, with all the genes together, this is not true, and the ...

Confocal microscopic image shows mesenchymal stem cells (green) captured within nanovials (pink). The nanovial technology was developed by UCLA's Dino Di Carlo and colleagues. Credit: Shreya ...

While the central dogma of molecular biology outlines the linear flow of genetic information from DNA to RNA to proteins (black lines), glycomics introduces a “3rd code of life”—glycans—that operates ...