The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions via a process called cell fate determination. The fate of individual cells, ...

Metabolism regulates cell fates through the epigenome. Wang, Shi et al. demonstrate that the cell fates of pluripotency, differentiation and ageing emerge from how a nuclear protein channels metabolic ...

In multicellular organisms, the spatial organization and function of a variety of cell types is a direct consequence of information encoded in the genome. The specification of different cell fates ...

Scientists at the Stowers Institute for Medical Research, Helmholtz Munich, the Technical University of Munich, and the University of Oxford have developed RegVelo - a new AI framework that ...