Cancer cachexia is a common wasting syndrome in individuals with cancer that involves activation of PKA in white adipose tissue, but the mechanisms that control PKA activity are unclear. A study now ...

A comprehensive review outlines how malignant cells rewire nitrogen pathways to fuel proliferation, resist nutrient stress, ...

Researchers found that eukaryotic translation initiation factor 3 subunit I promotes gastric cancer progression by ...

Mukherjee is a physician, researcher, and author. He has co-founded several biotechnology and health care companies focused on developing novel cancer treatments, including Faeth Therapeutics and ...

A century after Otto Warburg first described the phenomenon where cancer cells undergo glycolysis instead of oxygen respiration—even in oxygen-rich environments—the so-called Warburg effect continues ...

AcTor was combined with ixazomib (IXZ), a drug used to inhibit cancer cell proliferation. Together, the treatments disrupt ...

Cancer cells have voracious appetites. And there are certain nutrients they can't live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of ...

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol ...

Dr. Charles Brenner studies the link between metabolism and disease. His habits include changing his workout routines so he doesn't get bored.

A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This was discovered by researchers at the Rudolf Virchow Centre at the University of Würzburg. The human body ...