Researchers looked specifically at head-to-head randomized clinical trials of next-in-class cancer drugs against existing agents in the same class. Less than one-quarter of next-in-class cancer drugs ...

Using rapid protein degradation, chemogenomics, and super‑resolution microscopy in mouse embryonic stem cells, the team dissected the distinct contributions of BRD2 and BRD4 to transcription.

For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The ...

SAN FRANCISCO (KGO) -- Bay Area researchers are fighting back against a particularly deadly form of cancer and they're doing it with a new generation of drugs. These drugs enlist the body's own immune ...

The drug can now be prescribed alongside nab-paclitaxel for patients with ovarian cancer who have relapsed between one and ...

WEST LAFAYETTE – Purdue University researcher Andrea Kasinski is developing a new class of cancer drugs using microRNAs, ...

China’s National Medical Products Administration (NMPA) has approved four new drugs developed by local biopharma companies, including a first-of-its-kind molecule in blood cancer. Wednesday, Chinese ...

Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release ...

Gilead said on Tuesday it would acquire private Germany-based Tubulis GmbH for up to $5 billion, as the U.S. drugmaker looks to boost its pipeline with a lucrative class of ...

Telmisartan, an FDA-approved blood pressure drug, could boost a certain cancer treatment's effectiveness against tumors, a ...

In 22.2% of trials, there was a survival benefit with the next-in-class agent. Less than one-quarter of next-in-class cancer drugs demonstrated a survival benefit over existing in-class agents in head ...