Studying over 100,000 embryos revealed genetic factors behind chromosome segregation issues that lead to aneuploidy, informing future risk screening and intervention.

Errors in chromosome segregation cause more than 80% of early human embryos to contain cells with an incorrect number of chromosomes, a phenomenon called aneuploidy. While aneuploid cells are normally ...

A research team led by Professor YANG Zhenye from the Division of Life Sciences and Medicine, the University of Science and Technology of China (USTC) of Chinese Academy of Sciences (CAS), in ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 29 (July 21, 2020), pp. 17031-17040 (10 pages) Aneuploidy, a condition characterized by whole chromosome ...

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the ...

What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity? This basic question has bothered cancer researchers ...

Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer ...

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the ...

Two complementary studies from the Faculty of Medical and Health Sciences at Tel Aviv University, in collaboration with the European Institute of Oncology in Milan, have extensively examined the ...