Detroit Lions wide receiver Amon-Ra St. Brown was a surprise addition to the injury report after missing practice on Wednesday.

Lions star WR Amon-Ra St. Brown missed Wednesday's practice with a wrist injury ahead of the Week 6 showdown against the Chiefs.

Lions' Al-Quadin Muhammad credits defensive line coach Kacy Rodgers with helping him better understand the mental aspects of the game.

According to DraftKings, Detroit enters its primetime showdown with the Kansas City Chiefs as 2.5-point underdogs, despite looking like the more complete team through five weeks. The Lions are coming off a 37-24 victory over the Cincinnati Bengals, a game that showcased their offensive balance and defensive resilience.

NFL network analysts Brian Baldinger and Bucky Brooks analyze the Detroit Lions and Kansas City Chiefs offenses ahead of Week 6 matchup.

The Kansas City Chiefs play a big game against the Detroit Lions on Sunday night. Patrick Mahomes can make NFL history.

The Detroit Lions have won four of their first five games to start the 2025-26 NFL season and are coming off of a solid road showing in Cincinnati. The Lions’ win over the Bengals didn’t come without a cost as starting quarterback Terrion Arnold went down with a shoulder injury that was initially feared to be season ending.

Overall picks to win: 7-7 in Week 4 (53-24-1 for the season) Picks to win with 1-5 confidence: 5-5 (34-18-1) Picks to win with 6-10 confidence: 2-2 (19-6) Overall to cover the spread: 7-7 (38-37-3) Cover the spread picks with 1-5 confidence: 5-6 (32-31-2) Cover the spread picks with 6-10 confidence: 2-1 (6-6-1)

The Lions have the highest scoring offense in the league as they are averaging 34.8 points per game. They should be able to come close to that level against the Chiefs. Goff will throw three TD passes in the game, connecting with St. Brown, Williams and Sam LaPorta as he torments the vaunted Kansas City defense.